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The Invesco Biotechnology & Genome ETF (PBE) seeks to replicate the performance of the Dynamic Biotech & Genome Intellidex Index. This fund typically allocates a minimum of 90% of its total assets to the securities comprising the underlying index. The Index is constructed to achieve capital appreciation by thoroughly evaluating companies based on several investment criteria, including their price momentum, earnings growth, overall quality, management decisions, and valuation. It consists of 30 U.S.-based companies within the biotechnology and genome sectors. These companies are primarily involved in the research, development, manufacture, and distribution of various biotechnological products, services, and processes, or they are businesses that stand to gain significantly from scientific and technological breakthroughs in biotechnology and genetic engineering. Both the ETF and its benchmark index undergo quarterly rebalancing and reconstitution in February, May, August, and November.
| Symbol | Name | Weight | Market Value |
|---|---|---|---|
| VRTX | Vertex Pharmaceuticals Inc | 5.19% | $14.44M |
| BIIB | Biogen Inc | 5.08% | $14.13M |
| AMGN | Amgen Inc | 4.86% | $13.52M |
| RPRX | Royalty Pharma PLC | 4.80% | $13.35M |
| REGN | Regeneron Pharmaceuticals Inc | 4.51% | $12.54M |
| ALNY | Alnylam Pharmaceuticals Inc | 4.50% | $12.51M |
| GILD | Gilead Sciences Inc | 4.28% | $11.90M |
| UTHR | United Therapeutics Corp | 4.27% | $11.87M |
| TECH | Bio-Techne Corp | 3.65% | $10.16M |
| VCYT | Veracyte Inc | 3.36% | $9.35M |
| CDNA | CareDx Inc | 3.36% | $9.34M |
| VCEL | Vericel Corp | 3.18% | $8.86M |
| ILMN | Illumina Inc | 3.08% | $8.57M |
| PTGX | Protagonist Therapeutics Inc | 3.01% | $8.36M |
| PTCT | PTC Therapeutics Inc | 2.98% | $8.28M |
| RGEN | Repligen Corp | 2.94% | $8.17M |
| ACAD | ACADIA Pharmaceuticals Inc | 2.93% | $8.14M |
| INCY | Incyte Corp | 2.92% | $8.11M |
| ANAB | AnaptysBio Inc | 2.82% | $7.85M |
| BCRX | BioCryst Pharmaceuticals Inc | 2.79% | $7.75M |
| HALO | Halozyme Therapeutics Inc | 2.77% | $7.72M |
| — | QIAGEN NV | 2.77% | $7.69M |
| NBIX | Neurocrine Biosciences Inc | 2.70% | $7.50M |
| BMRN | BioMarin Pharmaceutical Inc | 2.69% | $7.49M |
| EXEL | Exelixis Inc | 2.68% | $7.46M |