The largest US-listed Biotechnology companies, ranked by market capitalization. Market cap and sector are shown for each company.
| # | Company | Market cap | Sector |
|---|---|---|---|
| 1 | Vertex Pharmaceuticals IncorporatedVRTX | $126.4B | Healthcare |
| 2 | Regeneron Pharmaceuticals, Inc.REGN | $64.36B | Healthcare |
| 3 | argenx SEARGX | $56.28B | Healthcare |
| 4 |
| $41.29B |
| Healthcare |
| 5 | Alnylam Pharmaceuticals, Inc.ALNY | $40.28B | Healthcare |
|---|
| 6 | Revolution Medicines, Inc.RVMD | $39.86B | Healthcare |
|---|
| 7 | BeOne Medicines AGONC | $31.07B | Healthcare |
|---|
| 8 | Moderna, Inc.MRNA | $28.77B | Healthcare |
|---|
| 9 | Roivant Sciences Ltd.ROIV | $25.20B | Healthcare |
|---|
| 10 | BioNTech SEBNTX | $23.75B | Healthcare |
|---|
| 11 | United Therapeutics CorporationUTHR | $23.22B | Healthcare |
|---|
| 12 | Insmed IncorporatedINSM | $23.19B | Healthcare |
|---|
| 13 | Incyte CorporationINCY | $22.74B | Healthcare |
|---|
| 14 | Genmab A/SGMAB | $16.97B | Healthcare |
|---|
| 15 | Neurocrine Biosciences, Inc.NBIX | $16.87B | Healthcare |
|---|
| 16 | Ascendis Pharma A/SASND | $16.63B | Healthcare |
|---|
| 17 | Jazz Pharmaceuticals plcJAZZ | $14.92B | Healthcare |
|---|
| 18 | BridgeBio Pharma, Inc.BBIO | $14.60B | Healthcare |
|---|
| 19 | Exelixis, Inc.EXEL | $13.56B | Healthcare |
|---|
| 20 | Ionis Pharmaceuticals, Inc.IONS | $13.09B | Healthcare |
|---|
| 21 | Axsome Therapeutics, Inc.AXSM | $12.38B | Healthcare |
|---|
| 22 | Madrigal Pharmaceuticals, Inc.MDGL | $11.86B | Healthcare |
|---|
| 23 | Arrowhead Pharmaceuticals, Inc.ARWR | $11.33B | Healthcare |
|---|
| 24 | BioMarin Pharmaceutical Inc.BMRN | $11.18B | Healthcare |
|---|
| 25 | Summit Therapeutics Inc.SMMT | $11.16B | Healthcare |
|---|
| 26 | Bio-Techne CorporationTECH | $11.12B | Healthcare |
|---|
| 27 | Krystal Biotech, Inc.KRYS | $10.95B | Healthcare |
|---|
| 28 | Cytokinetics, IncorporatedCYTK | $10.61B | Healthcare |
|---|
| 29 | ImmunityBio, Inc.IBRX | $9.64B | Healthcare |
|---|
| 30 | Corcept Therapeutics IncorporatedCORT | $9.50B | Healthcare |
|---|
| 31 | Kymera Therapeutics, Inc.KYMR | $9.39B | Healthcare |
|---|
| 32 | Halozyme Therapeutics, Inc.HALO | $9.13B | Healthcare |
|---|
| 33 | Nuvalent, Inc.NUVL | $9.09B | Healthcare |
|---|
| 34 | Abivax S.A.ABVX | $8.69B | Healthcare |
|---|
| 35 | Alkermes plcALKS | $8.62B | Healthcare |
|---|
| 36 | TG Therapeutics, Inc.TGTX | $8.19B | Healthcare |
|---|
| 37 | Apogee Therapeutics, Inc.APGE | $8.19B | Healthcare |
|---|
| 38 | Vaxcyte, Inc.PCVX | $8.10B | Healthcare |
|---|
| 39 | Protagonist Therapeutics, Inc.PTGX | $8.05B | Healthcare |
|---|
| 40 | Immunovant, Inc.IMVT | $7.83B | Healthcare |
|---|
| 41 | Rhythm Pharmaceuticals, Inc.RYTM | $7.57B | Healthcare |
|---|
| 42 | Liquidia CorporationLQDA | $7.05B | Healthcare |
|---|
| 43 | Praxis Precision Medicines, Inc.PRAX | $6.76B | Healthcare |
|---|
| 44 | PTC Therapeutics, Inc.PTCT | $6.75B | Healthcare |
|---|
| 45 | Cogent Biosciences, Inc.COGT | $6.58B | Healthcare |
|---|
| 46 | Scholar Rock Holding CorporationSRRK | $6.33B | Healthcare |
|---|
| 47 | Centessa Pharmaceuticals plcCNTA | $6.27B | Healthcare |
|---|
| 48 | Ligand Pharmaceuticals IncorporatedLGND | $6.25B | Healthcare |
|---|
| 49 | CG Oncology Inc.CGON | $6.25B | Healthcare |
|---|
| 50 | Mirum Pharmaceuticals, Inc.MIRM | $6.05B | Healthcare |
|---|
| 51 | Belite Bio, IncBLTE | $5.70B | Healthcare |
|---|
| 52 | Erasca, Inc.ERAS | $5.57B | Healthcare |
|---|
| 53 | Legend Biotech CorporationLEGN | $5.53B | Healthcare |
|---|
| 54 | Spyre Therapeutics, Inc.SYRE | $5.37B | Healthcare |
|---|
| 55 | Veradermics, IncorporatedMANE | $5.37B | Healthcare |
|---|
| 56 | CRISPR Therapeutics AGCRSP | $5.36B | Healthcare |
|---|
| 57 | Caris Life Sciences, Inc.CAI | $5.30B | Healthcare |
|---|
| 58 | Travere Therapeutics, Inc.TVTX | $5.24B | Healthcare |
|---|
| 59 | Celcuity Inc.CELC | $5.10B | Healthcare |
|---|
| 60 | Xenon Pharmaceuticals Inc.XENE | $4.76B | Healthcare |
|---|
| 61 | Definium Therapeutics, Inc.DFTX | $4.73B | Healthcare |
|---|
| 62 | Viking Therapeutics, Inc.VKTX | $4.35B | Healthcare |
|---|
| 63 | ACADIA Pharmaceuticals Inc.ACAD | $4.32B | Healthcare |
|---|
| 64 | NewAmsterdam Pharma Company N.V.NAMSW | $4.26B | Healthcare |
|---|
| 65 | Edgewise Therapeutics, Inc.EWTX | $4.21B | Healthcare |
|---|
| 66 | Denali Therapeutics Inc.DNLI | $4.12B | Healthcare |
|---|
| 67 | NewAmsterdam Pharma Company N.V.NAMS | $4.11B | Healthcare |
|---|
| 68 | Crinetics Pharmaceuticals, Inc.CRNX | $4.08B | Healthcare |
|---|
| 69 | Telix Pharmaceuticals LimitedTLX | $4.01B | Healthcare |
|---|
| 70 | Catalyst Pharmaceuticals, Inc.CPRX | $3.85B | Healthcare |
|---|
| 71 | Dianthus Therapeutics, Inc.DNTH | $3.77B | Healthcare |
|---|
| 72 | Dyne Therapeutics, Inc.DYN | $3.60B | Healthcare |
|---|
| 73 | Adaptive Biotechnologies CorporationADPT | $3.58B | Healthcare |
|---|
| 74 | Tango Therapeutics, Inc.TNGX | $3.58B | Healthcare |
|---|
| 75 | Oruka Therapeutics, Inc.ORKA | $3.49B | Healthcare |
|---|
| 76 | Enliven Therapeutics, Inc.ELVN | $3.48B | Healthcare |
|---|
| 77 | Beam Therapeutics Inc.BEAM | $3.44B | Healthcare |
|---|
| 78 | IDEAYA Biosciences, Inc.IDYA | $3.44B | Healthcare |
|---|
| 79 | Alumis Inc.ALMS | $3.29B | Healthcare |
|---|
| 80 | Arcutis Biotherapeutics, Inc.ARQT | $3.23B | Healthcare |
|---|
| 81 | Ultragenyx Pharmaceutical Inc.RARE | $3.19B | Healthcare |
|---|
| 82 | Relay Therapeutics, Inc.RLAY | $3.11B | Healthcare |
|---|
| 83 | Vera Therapeutics, Inc.VERA | $3.06B | Healthcare |
|---|
| 84 | Structure Therapeutics Inc.GPCR | $3.00B | Healthcare |
|---|
| 85 | GRAIL Inc.GRAL | $2.92B | Healthcare |
|---|
| 86 | Arcus Biosciences, Inc.RCUS | $2.91B | Healthcare |
|---|
| 87 | Disc Medicine, Inc.IRON | $2.86B | Healthcare |
|---|
| 88 | uniQure N.V.QURE | $2.82B | Healthcare |
|---|
| 89 | AnaptysBio, Inc.ANAB | $2.82B | Healthcare |
|---|
| 90 | Kailera Therapeutics, Inc.KLRA | $2.70B | Healthcare |
|---|
| 91 | Tarsus Pharmaceuticals, Inc.TARS | $2.62B | Healthcare |
|---|
| 92 | Trevi Therapeutics, Inc.TRVI | $2.50B | Healthcare |
|---|
| 93 | SELLAS Life Sciences Group, Inc.SLS | $2.47B | Healthcare |
|---|
| 94 | Celldex Therapeutics, Inc.CLDX | $2.45B | Healthcare |
|---|
| 95 | Pharvaris N.V.PHVS | $2.37B | Healthcare |
|---|
| 96 | AbCellera Biologics Inc.ABCL | $2.32B | Healthcare |
|---|
| 97 | Vericel CorporationVCEL | $2.31B | Healthcare |
|---|
| 98 | Agios Pharmaceuticals, Inc.AGIO | $2.21B | Healthcare |
|---|
| 99 | Zai Lab LimitedZLAB | $2.16B | Healthcare |
|---|
| 100 | Kardigan, Inc.KARD | $2.15B | Healthcare |
|---|
Showing the top 100 companies.
